Vishay Intertechnology finalised the purchase of Nexperia's facility and operations in the city in March for $177m.
Now it is investing in Newport Wafer Fab in a move aimed at bringing in new product range capabilities and skilled job opportunities to Newport.
The investment has been supported by £5m of Welsh Government funding.
It is the latest in a long list of good news for the South Wales compound semiconductor cluster – which continues to attract international interest and recognition.
Welsh Government economy, energy and planning cabinet secretary Rebecca Evans said: "Compound semiconductors are all around us – in our homes and in our phones, our trains and our turbines. They are a vital, if miniature, piece of what makes the modern world tick, with extremely strong global growth projections. And we in Wales are increasingly a world-leading nation in their production and manufacture.
“Today that is more evident than ever, with our international reputation attracting significant inward investment, the provision and occupation of state-of-the-art facilities, clear links with R&D and well-paid opportunities for employment and apprenticeships.
“We are now, after a decade of seeding the cluster, reaping the rewards of our commitment which we will continue to drive forward.”